ALKBH4 antibody

• Background:

  Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation.

• Synonyms:

  Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4|Alkylated DNA repair protein alkB homolog 4|DNA N6-methyl adenine demethylase ALKBH4|Lysine-specific demethylase ALKBH4|ALKBH4|ABH4

• Gene ID:

  54784

• UniProt:

  Q9NXW9

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  AlkB, alkylation repair homolog 4 (E. coli)

• Target:

  ALKBH4

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IF

• Field of Research:

  Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:200-1:2000; IHC: 1:10-1:100

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  34 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IF