Infliximab (Anti-TNF-α)

CAT:

804-HY-P9970A-01

Size:

1 mg

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UNSPSC Description: Infliximab (Anti-TNF-α) (Avakine (Anti-TNF-α)) is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α. Infliximab (Anti-TNF-α) prevents the interaction of TNF-α with TNF-α receptor (TNFR1 and TNFR2). Infliximab (Anti-TNF-α) has the potential for autoimmune, chronic inflammatory diseases and diabetic neuropathy research[1][2].
Target Antigen: TNF Receptor
Type: Inhibitory Antibodies
Related Pathways: Apoptosis
Applications: Metabolism-sugar/lipid metabolism
Field of Research: Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol: https://www.medchemexpress.com/infliximab-anti-tnf-α.html
Purity: 99.00
Smiles: [Infliximab (Anti-TNF-a)]
References & Citations: [1]Lucia A Méndez-García, et al. Infliximab ameliorates tumor necrosis factor-alpha-induced insulin resistance by attenuating PTP1B activation in 3T3L1 adipocytes in vitro. Scand J Immunol. 2018 Nov;88(5):e12716. |[2]Isamu Yamakawa, et al. Inactivation of TNF-α ameliorates diabetic neuropathy in mice. Am J Physiol Endocrinol Metab. 2011 Nov;301(5):E844-52.
Shipping Conditions: Dry Ice
Storage Conditions: Store at -80°C for 2 years
Clinical Information: No Development Reported

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