Infliximab
CAT:
804-HY-P9970-03
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: Yes
Infliximab
- CAS Number: 170277-31-3
- UNSPSC Description: Infliximab (Avakine) is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α. Infliximab prevents the interaction of TNF-α with TNF-α receptor (TNFR1 and TNFR2). Infliximab has the potential for autoimmune, chronic inflammatory diseases and diabetic neuropathy research[1][2].
- Target Antigen: TNF Receptor
- Type: Inhibitory Antibodies
- Related Pathways: Apoptosis
- Applications: Metabolism-sugar/lipid metabolism
- Field of Research: Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/infliximab.html
- Purity: 90.30
- Solubility: H2O : 100 mg/mL (ultrasonic)
- Smiles: [Infliximab]
- References & Citations: [1]Lucia A Méndez-García, et al. Infliximab ameliorates tumor necrosis factor-alpha-induced insulin resistance by attenuating PTP1B activation in 3T3L1 adipocytes in vitro. Scand J Immunol. 2018 Nov;88(5):e12716.|[2]Isamu Yamakawa, et al. Inactivation of TNF-α ameliorates diabetic neuropathy in mice. Am J Physiol Endocrinol Metab. 2011 Nov;301(5):E844-52.
- Shipping Conditions: Dry Ice
- Storage Conditions: Store at -80°C for 2 years
- Clinical Information: Launched