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Guanethidine (sulfate)

CAT: 0804-HY-B0800-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0800-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Guanethidine sulfate (Guanethidine monosulfate), an antihypertensive agent, is an adrenergic neurone blocking agent. Guanethidine sulfate enters noradrenergic nerve terminals by the neuronal amine carrier[1][2].
CAS Number
645-43-2
Product Name Alternative
Guanethidine monosulfate
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Guanethidine-sulfate.html
Purity
98.0
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
NC(NCCN1CCCCCCC1)=N.O=S(O)(O)=O
Molecular Formula
C10H24N4O4S
Molecular Weight
296.39
Precautions
H302, H315, H319, H335
References & Citations
[1]Mitchell JR, et al. Antagonism of the antihypertensive action of guanethidine sulfate by desipramine hydrochloride. JAMA. 1967 Dec 4;202 (10) :973-6.|[2]Nielsen GD. Guanethidine induced sympathectomy in the adult rat. I. Functional effects following subacute administration. Acta Pharmacol Toxicol (Copenh) . 1977 Sep;41 (3) :203-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched

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B8683-1000Guanethidine (sulfate)
317983Guanethidine Sulfate
278377-01Guanethidine sulfate discontinued. See 451506
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