Guanethidine

• Description:

  Guanethidine sulphate was synthesized in 1959. Guanethidine is thought to lowing blood pressure by interfering with the metabolism of chemical transmitter substances in post-ganglionic sympathetic nerve fibres.

• UNSPSC:

  12352005

• Target:

  Adrenergic Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Field of Research:

  Neurological Disease; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/guanethidine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NC(NCCN1CCCCCCC1)=N

• Molecular Formula:

  C10H22N4

• Molecular Weight:

  198.31

• References & Citations:

  [1]P Dubový, etal. Local chemical sympathectomy of rat bone marrow and its effect on marrow cell composition.|[2]Waldiceu A.VerriJr, etal. Antigen-induced inflammatory mechanical hypernociception in mice is mediated by IL-18. Brain Beha

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• CAS Number:

  [55-65-2]