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Guanethidine

CAT: 0804-HY-B1251Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-B1251Size:1 Each
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Description
Guanethidine sulphate was synthesized in 1959. Guanethidine is thought to lowing blood pressure by interfering with the metabolism of chemical transmitter substances in post-ganglionic sympathetic nerve fibres.
CAS Number
[55-65-2]
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/guanethidine.html
Solubility
10 mM in DMSO
Smiles
NC(NCCN1CCCCCCC1)=N
Molecular Formula
C10H22N4
Molecular Weight
198.31
References & Citations
[1]P Dubový, etal. Local chemical sympathectomy of rat bone marrow and its effect on marrow cell composition.|[2]Waldiceu A.VerriJr, etal. Antigen-induced inflammatory mechanical hypernociception in mice is mediated by IL-18. Brain Beha
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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