Ianthelliformisamine A (TFA)

• CAS Number:

  1643593-28-5

• UNSPSC Description:

  Ianthelliformisamine A TFA is an antibiotic enhancer with activity against resistant Gram-negative bacteria. Ianthelliformisamine A TFA exhibits bactericidal activity against Staphylococcus aureus with an IC50 value of 3.8 μM (minimum inhibitory concentration = 25 μM). The biological activity of Ianthelliformisamine A TFA is derived from the structural variation of its synthetic derivatives and its coupling reaction with different amino ester derivatives[1].

• Target Antigen:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/ianthelliformisamine-a-tfa.html

• Smiles:

  OC(C(F)(F)F)=O.NCCCNCCCCNCCCNC(/C=C/C1=CC(Br)=C(C(Br)=C1)OC)=O

• Molecular Weight:

  634.33

• References & Citations:

  [1]Synthesis and antibacterial activities of marine natural product ianthelliformisamines and subereamine synthetic analogues

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 3