Fosamprenavir

Fosamprenavir

• CAS Number: 226700-79-4
• UNSPSC Description: Fosamprenavir (Amprenavir phosphate;GW 433908) is a phosphate ester proagent of the antiretroviral protease inhibitor Amprenavir, with improved solubility[1]. Anti-HIV infection[1].
• Target Antigen: Endogenous Metabolite; HIV
• Type: Reference compound
• Related Pathways: Anti-infection;Metabolic Enzyme/Protease
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/Fosamprenavir.html
• Purity: 99.94
• Solubility: DMSO : ≥ 100 mg/mL
• Smiles: O=C(O[C@@H]1COCC1)N[C@@H](CC2=CC=CC=C2)[C@H](OP(O)(O)=O)CN(S(=O)(C3=CC=C(N)C=C3)=O)CC(C)C
• Molecular Weight: 585.61
• References & Citations: [1]Falcoz C, et al. Pharmacokinetics of GW433908, a prodrug of amprenavir, in healthy male volunteers. J Clin Pharmacol. 2002 Aug;42(8):887-98.Antimicrob Agents Chemother. 2020 Aug 20;64(9):e00872-20.|Nat Commun. 2020 Sep 4;11(1):4417.|Research Square Print. 2022 May.|Int J Antimicrob Agents. 2019 Dec;54(6):814-819.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: Launched