Fosamprenavir-d4

Fosamprenavir-d4

• CAS Number: 1133702-41-6
• UNSPSC Description: Fosamprenavir-d4 is deuterium labeled Fosamprenavir. Fosamprenavir (Amprenavir phosphate;GW 433908) is a phosphate ester proagent of the antiretroviral protease inhibitor Amprenavir, with improved solubility[1]. Anti-HIV infection[1].
• Target Antigen: Endogenous Metabolite; HIV; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Anti-infection;Metabolic Enzyme/Protease;Others
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Solubility: 10 mM in DMSO
• Smiles: O=C(O[C@H]1CCOC1)N[C@@H](CC2=CC=CC=C2)[C@H](OP(O)(O)=O)CN(CC(C)C)S(=O)(C3=C([2H])C([2H])=C(C([2H])=C3[2H])N)=O
• Molecular Weight: 589.63
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Falcoz C, et al. Pharmacokinetics of GW433908, a prodrug of amprenavir, in healthy male volunteers. J Clin Pharmacol. 2002 Aug;42(8):887-98.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported