Fosamprenavir (Calcium Salt)

Fosamprenavir (Calcium Salt)

• CAS Number: 226700-81-8
• UNSPSC Description: Fosamprenavir Calcium Salt (GW433908G) is a phosphate ester proagent of the antiretroviral protease inhibitor Amprenavir, with improved solubility[1]. Anti-HIV infection[1].
• Target Antigen: Endogenous Metabolite; HIV
• Type: Reference compound
• Related Pathways: Anti-infection;Metabolic Enzyme/Protease
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/fosamprenavir-calcium-salt.html
• Solubility: DMSO : 50 mg/mL (ultrasonic)|H2O : 0.25 mg/mL (ultrasonic;warming)
• Smiles: O=C(O[C@@H]1COCC1)N[C@@H](CC2=CC=CC=C2)[C@H](OP([O-])([O-])=O)CN(S(=O)(C3=CC=C(N)C=C3)=O)CC(C)C.[Ca+2]
• Molecular Weight: 623.67
• References & Citations: [1]Falcoz C, et al. Pharmacokinetics of GW433908, a prodrug of amprenavir, in healthy male volunteers. J Clin Pharmacol. 2002 Aug;42(8):887-98.Int J Antimicrob Agents. 2019 Dec;54(6):814-819.|Antimicrob Agents Chemother. 2020 Aug 20;64(9):e00872-20.|Nat Commun. 2020 Sep 4;11(1):4417.|Research Square Print. 2022 May.
• Shipping Conditions: Room Temperature
• Clinical Information: Launched