PE-Labeled Human HLA-A*03:01&B2M&KRASG12V (VVGAVGVGK) Tetramer Protein

PE-Labeled Human HLA-A*03:01&B2M&KRASG12V (VVGAVGVGK) Tetramer Protein

• Background: The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention. The Biotinylated Human HLA-A*0301 KRASG12V (VVGAVGVGK) complex protein is a complex of HLA-A*0301 of the MHC Class I, B2M, and VVGAVGVGK peptide of the KRASG12V.
• Description: PE-Labeled Human HLA-A*03:01&B2M&KRASG12V (VVGAVGVGK) Tetramer Protein (HLV-HP2H8) is expressed from human 293 cells (HEK293). It contains AA Gly 25 -Thr 305 (HLA-A*03:01) & Ile 21 - Met 119 (B2M) & VVGAVGVGK peptide (Accession # P04439-1 (HLA-A*03:01) & P61769 (B2M) & VVGAVGVGK).
• Specifications: PE-Labeled Human HLA-A*03:01&B2M&KRASG12V (VVGAVGVGK) Tetramer Protein is assembled by biotinylated monomer (HLV-H82E9) and PE-labeled streptavidin. Biotinylated Human HLA-A*03:01&B2M&KRASG12V (VVGAVGVGK) Complex Protein is produced by co-expression of HLA and B2M loaded with KRASG12V peptide. Biotinylated Human HLA-A*03:01&B2M&KRASG12V (VVGAVGVGK) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).
• Expression Region: Gly 25 -Thr 305 (HLA-A*03:01) & Ile 21 - Met 119 (B2M) & VVGAVGVGK peptide
• Host: HEK 293
• Target: HLA-A*0301 & B2M & KRASG12V (VVGAVGVGK)
• Conjugation: PE Labeled
• Tag: C-10×His
• Source: Human
• Stability: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Endotoxin: 1.0 EU per μg
• Format: Powder
• Buffer: PBS, 1% BSA, pH7.4
• Additives: Trehalose
• Molecular Weight: 36.1 kDa and 11.7 kDa
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, aviod light