ω-Hexatoxin-Hv1a
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804-HY-P5142
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ω-Hexatoxin-Hv1a
- CAS Number: 193981-10-1
- UNSPSC Description: ω-Hexatoxin-Hv1a is a neurotoxin that can be isolated from the venom spider (Hadronyche versuta).ω-Hexatoxin-Hv1a blocks voltage-gated calcium channels[1][2].
- Target Antigen: Calcium Channel
- Type: Peptides
- Related Pathways: Membrane Transporter/Ion Channel;Neuronal Signaling
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/ω-hexatoxin-hv1a.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(N1[C@@H](CCC1)C(N[C@@H]([C@H](O)C)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@H]2CO)=O)=O)=O)NC3=O)C(N[C@@H]([C@@H](C)CC)C(N4[C@@H](CCC4)C(N[C@@H](CO)C(NCC(N[C@@H](CCC(N)=O)C(N5[C@@H](CCC5)C(N[C@@H](CSSC[C@@H](C(N[C@@H]([C@H](O)C)C(N[C@@H](CC6=CC=CC=C6)C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(N)=O)C(NCC(N[C@@H](CC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@H]7CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC2=O)C(N8[C@@H](CCC8)C(N[C@@H](CC9=CC=C(C=C9)O)C(N[C@@H](CC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@H]3CSSC[C@@H](C(N[C@@H](CC(O)=O)C(O)=O)=O)NC7=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CO)N
- Molecular Weight: 4049.38
- References & Citations: [1]Powell ME, et al. Demonstrating the potential of a novel spider venom-based biopesticide for target-specific control of the small hive beetle, a serious pest of the European honeybee. J Pest Sci (2004). 2020;93(1):391-402.|[2]Yang S, et al. Effect of insecticidal fusion proteins containing spider toxins targeting sodium and calcium ion channels on pyrethroid-resistant strains of peach-potato aphid (Myzus persicae). Pest Manag Sci. 2015 Jul;71(7):951-6.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported