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6-Hydroxykaempferol

CAT: 0804-HY-116750-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-116750-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
6-Hydroxykaempferol, a flavonoid, is a competitive tyrosinase inhibitor with an IC50 value of 124 μM. 6-Hydroxykaempferol has a Ki value of 148 μM relative to L-DOPA as a substrate and effectively inhibits the activity of the enzyme by binding to the active site of the enzyme[1].
CAS Number
4324-55-4
UNSPSC
12352005
Target
Tyrosinase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/6-hydroxykaempferol.html
Solubility
10 mM in DMSO
Smiles
O=C1C(O)=C(C2=CC=C(O)C=C2)OC3=CC(O)=C(O)C(O)=C13
Molecular Formula
C15H10O7
Molecular Weight
302.24
References & Citations
[1]Hong Gao, et al. Inhibitory effects of 5,6,7-trihydroxyflavones on tyrosinase. Molecules. 2007 Jan 29;12 (1) :86-97.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported