6-Hydroxykaempferol

• Description:

  6-Hydroxykaempferol, a flavonoid, is a competitive tyrosinase inhibitor with an IC50 value of 124 μM. 6-Hydroxykaempferol has a Ki value of 148 μM relative to L-DOPA as a substrate and effectively inhibits the activity of the enzyme by binding to the active site of the enzyme[1].

• UNSPSC:

  12352005

• Target:

  Tyrosinase

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/6-hydroxykaempferol.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C(O)=C(C2=CC=C(O)C=C2)OC3=CC(O)=C(O)C(O)=C13

• Molecular Formula:

  C15H10O7

• Molecular Weight:

  302.24

• References & Citations:

  [1]Hong Gao, et al. Inhibitory effects of 5,6,7-trihydroxyflavones on tyrosinase. Molecules. 2007 Jan 29;12 (1) :86-97.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [4324-55-4]