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BACE-IN-1

CAT: 0804-HY-U00287Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-U00287Size:1 Each
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Description
BACE-IN-1 (Compound 13) is a substituted lmidazo[1 ,2-a]pyridine derivative which can inhibit β-site amyloid precursor protein-cleaving enzyme (BACE) and that may be useful in the treatment of diseases in which BACE is involved, such as Alzheimer's disease.
CAS Number
1254166-60-3
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Beta-secretase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Imidazo[1,2-a]pyridine-2-carboxamide,_6-chloro-N-[6-_phenylmethoxy_-1H-benzimidazol-2-yl]-.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CN2C=C(Cl)C=CC2=N1)NC3=NC4=CC=C(OCC5=CC=CC=C5)C=C4N3
Molecular Formula
C22H16ClN5O2
Molecular Weight
417.85
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501
References & Citations
[1]Adnan M.M. Mjalli, et al. SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE AS β-SECRETASE INHIBITORS. WO 2010126745 A1
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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