Jionoside A1

CAT: 0804-HY-N5045-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N5045-01Size:1 mg
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Jionoside A1 isolated from Radix Rehmanniae Praeparata displays dose dependent immune-enhancement activity and possesses moderate protective activities on H2O2-treated SH-SY5Y cells[1]. Jionoside A1 has neuroprotective effects and can alleviate the symptoms of ischemic stroke.
CAS Number
[120444-60-2]
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/jionoside-a1.html
Purity
98.58
Solubility
10 mM in DMSO
Smiles
COC1=C(O)C=CC(/C=C/C(O[C@H]2[C@@H]([C@H]([C@H](OCCC3=CC(O)=C(O)C=C3)O[C@@H]2CO[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)CO)O)O[C@@]5([H])[C@@H]([C@@H]([C@@H](O)[C@H](C)O5)O)O)=O)=C1
Molecular Formula
C36H48O20
Molecular Weight
800.75
References & Citations
[1]Shen L, et al. Identification of bioactive ingredients with immuno-enhancement and anti-oxidative effects from Fufang-Ejiao-Syrup by LC-MS (n) combined with bioassays. J Pharm Biomed Anal. 2016 Jan 5;117:363-71.|[2]Yu X, Liu X, Mi X, et al. Jionoside A1 alleviates ischemic stroke ischemia/reperfusion injury by promoting Nix-mediated mitophagy. Cell Mol Biol (Noisy-le-grand) . 2023;69 (8) :237-245.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Popular Products