Jionoside D

• Description:

  Jionoside D is a hydroxycinnamic acid ester with antioxidant property. Jionoside D has scavenging activity of intracellular reactive oxygen species (ROS) and of DPPH radical, and lipid peroxidation inhibitory activity. Jionoside D reduces the apoptotic cells induced by H2O2 in V79-4 cells. Jionoside D increases the activities of cellular antioxidant enzymes, SOD and catalase[1][2].

• UNSPSC:

  12352005

• Target:

  Apoptosis; Reactive Oxygen Species (ROS)

• Type:

  Natural Products

• Related Pathways:

  Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/jionoside-d.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@@H]1[C@@H](O)[C@@H](O)[C@@](O[C@@H]2[C@@H](O)[C@H](OCCC3=CC=C(OC)C(O)=C3)O[C@H](CO)[C@H]2OC(/C=C/C4=CC=C(O)C(O)=C4)=O)([H])O[C@H]1C

• Molecular Formula:

  C30H38O15

• Molecular Weight:

  638.61

• References & Citations:

  [1]Sasaki H, et al. Hydroxycinnamic acid esters of phenethylalcohol glycosides from Rehmannia glutinosa var. Purpurea[J]. Phytochemistry, 1989, 28 (3) :875-879.|[2]Chae S, et al. Antioxidant activity of jionoside D from Clerodendron trichotomum. Biol Pharm Bull. 2004 Oct;27 (10) :1504-8.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  120406-34-0