Norfloxacin (hydrochloride)

• UNSPSC Description:

  Norfloxacin hydrochloride (MK-0366 hydrochloride) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase.

• Target Antigen:

  Antibiotic; Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/norfloxacin-hydrochloride.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CN(CC)C2=C(C=C(F)C(N3CCNCC3)=C2)C1=O)O.Cl

• Molecular Weight:

  355.79

• References & Citations:

  [1]Nelson JM, et al. Fluoroquinolone-resistant Campylobacter species and the withdrawal of fluoroquinolones from use in poultry: a public health success story. Clin Infect Dis. 2007 Apr 1;44(7):977-80. Epub 2007 Feb 14.|[2]Padeiskaia EN. Norfloxacin: more than 20 years of clinical use, the results and place among fluoroquinolones in modern chemotherapy for infections. Antibiot Khimioter. 2003;48(9):28-36.|[3]Rafalsky V, et al. Quinolones for uncomplicated acute cystitis in women. Cochrane Database Syst Rev. 2006 Jul 19;(3):CD003597.Nat Commun. 2022 Mar 2;13(1):1116.|Theranostics. 2022 Jan 1;12(3):1187-1203.|Water Res. 2023 May 21, 120110.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Launched

• CAS Number:

  68077-27-0