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Norfloxacin

CAT: 0804-HY-B0132-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0132-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Norfloxacin (MK-0366) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase.
CAS Number
70458-96-7
Product Name Alternative
MK-0366
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Bacterial; Endogenous Metabolite
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Norfloxacin.html
Purity
99.0
Solubility
DMSO : 5 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
Smiles
O=C(C1=CN(CC)C2=C(C=C(F)C(N3CCNCC3)=C2)C1=O)O
Molecular Formula
C16H18FN3O3
Molecular Weight
319.33
Precautions
H302, H315, H319, H335
References & Citations
[1]Nelson JM, et al. Fluoroquinolone-resistant Campylobacter species and the withdrawal of fluoroquinolones from use in poultry: a public health success story. Clin Infect Dis. 2007 Apr 1;44 (7) :977-80. Epub 2007 Feb 14.|[2]Pade?skaia EN. Norfloxacin: more than 20 years of clinical use, the results and place among fluoroquinolones in modern chemotherapy for infections. Antibiot Khimioter. 2003;48 (9) :28-36.|[3]Rafalsky V, et al. Quinolones for uncomplicated acute cystitis in women. Cochrane Database Syst Rev. 2006 Jul 19; (3) :CD003597.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Quinolone
Citation 01
J Environ Qual. 2025 Oct 21.|Theranostics. 2022 Jan 1;12 (3) :1187-1203.|Water Res. 2023 Jul 15:240:120110.|Nat Commun. 2022 Mar 2;13 (1) :1116.

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