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Norfloxacin-d8

CAT: 0804-HY-B0132S1Size: 2.5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0132S1Size:2.5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Norfloxacin-d8 is the deuterium labeled Norfloxacin. Norfloxacin (MK-0366) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase.
CAS Number
1216601-32-9
Product Name Alternative
MK-0366-d8
UNSPSC
12352005
Target
Antibiotic; Bacterial; Endogenous Metabolite
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Solubility
10 mM in DMSO
Smiles
CCN1C2=CC(N3C([2H])([2H])C([2H])([2H])NC([2H])([2H])C3([2H])[2H])=C(F)C=C2C(C(C(O)=O)=C1)=O
Molecular Formula
C16H10D8FN3O3
Molecular Weight
327.38
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Nelson JM, et al. Fluoroquinolone-resistant Campylobacter species and the withdrawal of fluoroquinolones from use in poultry: a public health success story. Clin Infect Dis. 2007 Apr 1;44 (7) :977-80. Epub 2007 Feb 14.|[3]Pade?skaia EN. Norfloxacin: more than 20 years of clinical use, the results and place among fluoroquinolones in modern chemotherapy for infections. Antibiot Khimioter. 2003;48 (9) :28-36.|[4]Rafalsky V, et al. Quinolones for uncomplicated acute cystitis in women. Cochrane Database Syst Rev. 2006 Jul 19; (3) :CD003597.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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