Acitretin (sodium)

CAT: 0804-HY-B0107ASize: 1 EachDry Ice: NoHazardous: No

CAT#:0804-HY-B0107ASize:1 Each

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Description

Acitretin (Ro 10-1670) sodium is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. Acitretin sodium also can be used for the research of Alzheimer’s disease[1][2][3].

CAS Number

[925701-88-8]

Product Name Alternative

Ro 10-1670 (sodium)

UNSPSC

12352005

Target

Autophagy; RAR/RXR

Type

Reference compound

Related Pathways

Autophagy; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cancer

Assay Protocol

https://www.medchemexpress.com/Acitretin-sodium.html

Solubility

10 mM in DMSO

Smiles

CC(/C=C/C(C(C)=CC(OC)=C1C)=C1C)=C\C=C\C(C)=C\C(O[Na])=O

Molecular Formula

C21H25NaO3

Molecular Weight

348.41

References & Citations

[1]Lee CS, et al. A review of acitretin, a systemic retinoid for the treatment of psoriasis. Expert Opin Pharmacother. 2005 Aug;6 (10) :1725-34.|[2]Seng?r B, et al. Effects of acitretin on spermatogenesis of rats. J Eur Acad Dermatol Venereol. 2006 Jul;20 (6) :689-92.|[3]Guilherme MDS, et, al. The Synthetic Retinoid Acitretin Increases IL-6 in the Central Nervous System of Alzheimer Disease Model Mice and Human Patients. Front Aging Neurosci. 2019 Jul 23;11:182.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Launched

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A10035-500	Acitretin 500mg
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Acitretin (sodium)

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