13-cis Acitretin-d3

13-cis Acitretin-d3

• Product Name Alternative: Isoacitretin D3; Ro 13-7652 D3
• CAS Number: 1185241-03-5
• UNSPSC Description: 13-cis Acitretin-d3 is a deuterium labeled 13-cis Acitretin. 13-cis Acitretin is the metabolite of Acitretin after chronic administration. Acitretin(Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis[1][2].
• Target Antigen: Drug Metabolite; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease;Others
• Field of Research: Inflammation/Immunology
• Solubility: 10 mM in DMSO
• Smiles: O=C(/C=C(\C=C\C=C(\C=C\C1=C(C=C(C(C)=C1C)OC([2H])([2H])[2H])C)C)C)O
• Molecular Weight: 329.45
• References & Citations: [1]A E Stuck, et al. Pharmacokinetics of acitretin and its 13-cis metabolite in patients on haemodialysis. Br J Clin Pharmacol. 1989 Mar; 27(3): 301–304.|[2]Berbis P, et al. Residual plasma concentrations of acitretin (Ro 10-1670) and its metabolite (Ro 13-7652) after chronic administration. Dermatologica. 1988;177(4):244-6.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported