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Calcitriol Derivatives

CAT: 0804-HY-76802-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-76802-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Calcitriol Derivatives is a vitamin D3 analog. v
CAS Number
2070009-24-2
UNSPSC
12352211
Target
VD/VDR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/calcitriol-derivatives.html
Purity
99.66
Solubility
10 mM in DMSO
Smiles
O[C@H](C/1=C)C[C@@H](CC1=C\C=C2[C@@](CC[C@@H]3[C@@H](CCCC(C)(O)C)C)([H])[C@]3(C)CCC\2)OCCC#N
Molecular Formula
C30H47NO3
Molecular Weight
469.70
References & Citations
[1]Barrera D, Noyola-Martínez N, Avila E, Halhali A, Larrea F, Díaz L. Calcitriol inhibits interleukin-10 expression in cultured human trophoblasts under normal and inflammatory conditions. Cytokine. 2012 Mar;57 (3) :316-21.|[2]Lydia A, Asanuma K, Nonaka K, Takagi M, Jeong KH, Kodama F, Asao R, Asanuma E, Prodjosudjadi W, Tomino Y. Effects of 22-oxa-calcitriol on podocyte injury in adriamycin-induced nephrosis. Am J Nephrol. 2012;35 (1) :58-68.|[3]Michalak K, Wicha J. Total synthesis of a CD-ring: side-chain building block for preparing 17-epi-calcitriol derivatives from the Hajos-Parrish dione. J Org Chem. 2011 Aug 19;76 (16) :6906-11.|[4]Moorthi RN, Kandula P, Moe SM. Optimal vitamin D, calcitriol, and vitamin D analog replacement in chronic kidney disease: to D or not to D: that is the question. Curr Opin Nephrol Hypertens. 2011 Jul;20 (4) :354-9.|[5]Yu WD, Ma Y, Flynn G, Muindi JR, Kong RX, Trump DL, Johnson CS. Calcitriol enhances gemcitabine anti-tumor activity in vitro and in vivo by promoting apoptosis in a human pancreatic carcinoma model system. Cell Cycle. 2010 Aug 1;9 (15) :3022-9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported