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(S) - (-) -5-Fluorowillardiine

CAT: 0804-HY-16713Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-16713Size:1 Each
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Description
(S) - (-) -5-Fluorowillardiine is a potent and specific AMPAR agonist.
CAS Number
140187-23-1
Product Name Alternative
(5S) -Fluorowillardiine; (S) -5-Fluorowillardiine
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/_S_-_-_-5-Fluorowillardiine.html
Solubility
10 mM in DMSO
Smiles
OC([C@@H](N)CN1C=C(F)C(NC1=O)=O)=O
Molecular Formula
C7H8FN3O4
Molecular Weight
217.15
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Hawkinson JE, et al. Effects of thiocyanate and AMPA receptor ligands on (S) -5-fluorowillardiine, (S) -AMPA and (R, S) -AMPA binding. Eur J Pharmacol. 1997 Jun 25;329 (2-3) :213-21.|[2]Kessler M, et al. Use of [3H]fluorowillardiine to study properties of AMPA receptor allosteric modulators. Brain Res. 2006 Mar 3;1076 (1) :25-41.|[3]Rembach A, et al. Antisense peptide nucleic acid targeting GluR3 delays disease onset and progression in the SOD1 G93A mouse model of familial ALS. J Neurosci Res. 2004 Aug 15;77 (4) :573-82.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AMPA Receptor

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Alternative Products

CatalogName
T13480-01(S) - (-) -5-Fluorowillardiine
MBS3845767-01(S)-(-)-5-Fluorowillardiine
465114-01S- (-) -5-Fluorowillardiine
A21337-5(S) - (-) -5-Fluorowillardiine 5mg
A21337-50(S) - (-) -5-Fluorowillardiine 50mg
A21337-10(S) - (-) -5-Fluorowillardiine 10mg
A21337-1(S) - (-) -5-Fluorowillardiine 1mg
T13480L(S) - (-) -5-Fluorowillardiine hydrochloride
A21337-100(S) - (-) -5-Fluorowillardiine 100mg
A21337-2(S) - (-) -5-Fluorowillardiine 2mg

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