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Miriplatin (hydrate)

CAT: 0804-HY-16325Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-16325Size:1 Each
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Description
Miriplatin hydrate (SM-11355 hydrate) is a chemotherapy agent which belongs to the class of alkylating agents.
CAS Number
250159-48-9
Product Name Alternative
SM-11355 (hydrate)
UNSPSC
12352211
Target
DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/miriplatin-hydrate.html
Solubility
10 mM in DMSO
Smiles
NC1CCCCC1N.[O-]C(CCCCCCCCCCCCC)=O.[O-]C(CCCCCCCCCCCCC)=O.O.[Pt+2]
Molecular Formula
C34H70N2O5Pt
Molecular Weight
782.01
References & Citations
[1]Kishimoto S, et al. Antitumor effects of a novel lipophilic platinum complex (SM-11355) against a slowly-growing rat hepatic tumor after intra-hepatic arterial administration. Biol Pharm Bull. 2000 Mar;23 (3) :344-8.|[2]Hanada M, et al. Intra-hepatic arterial administration with miriplatin suspended in an oily lymphographic agent inhibits the growth of tumors implanted in rat livers by inducing platinum-DNA adducts to form and massive apoptosis. Cancer Chemother Pharmacol. 2009 Aug;64 (3) :473-83.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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