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Antibacterial agent 231

CAT: 0804-HY-162672Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162672Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Antibacterial agent 231 (derivative 8) is an antimicrobial agent against multidrug-resistant Helicobacter pylori (H. pylori) with a minimum inhibitory concentration of 0.25–0.5 μg/mL. Antibacterial agent 231 directly targets the protein transposase subunit SecA and the outer membrane protein assembly factor BamD to inhibit the trafficking and assembly of bacterial outer membrane proteins (OMPs) . Antibacterial agent 231 can be used to study the effects of antibiotic treatment on intestinal microbial balance[1].
CAS Number
9007-83-4
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-231.html
Smiles
COC1=C(OC/C=C/C)C=C2C(C(C(C/C=C/C)=C(C=CC(OC)=C3OC)C3=C4)=[N+]4CC2)=C1.[Br-]
Molecular Formula
C28H32BrNO4
Molecular Weight
526.46
References & Citations
[1]X Guo, et al. A deep learning-driven discovery of berberine derivatives as novel antibacterial against multidrug-resistant Helicobacter pylori. Signal Transduction and Targeted Therapy 9, no. 1 (2024) : 183.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported