Hoechst 34580

CAT: 0804-HY-15560-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-15560-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Hoechst 34580 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore, Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1].
CAS Number
[23555-00-2]
Product Name Alternative
HOE 34580
UNSPSC
12171500
Hazard Statement
H302
Target
Amyloid-β
Type
Dye Reagents
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Hoechst-34580.html
Purity
99.84
Solubility
DMSO : ≥ 47 mg/mL
Smiles
CN1CCN(C2=CC=C3C(N=C(C4=CC=C5C(N=C(C6=CC=C(N(C)C)C=C6)N5)=C4)N3)=C2)CC1
Molecular Formula
C27H29N7
Molecular Weight
451.57
Precautions
H302
References & Citations
[1]Thai NQ, et al. Discovery of DNA dyes Hoechst 34580 and 33342 as good candidates for inhibiting amyloid beta formation: in silico and in vitro study. J Comput Aided Mol Des. 2016 Aug;30 (8) :639-50.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Citation 01
Free Radic Biol Med. 2024 Sep 17:S0891-5849 (24) 00666-X.|J Lipid Res. 2023 Mar;64 (3) :100338.|Medical University of Vienna. 2025.|Microbiol Res. 2025 Jun 16:299:128259.|PLoS One. 2019 Mar 18;14 (3) :e0213794.

Related Products

CatalogName
HY-D2220SiR-Hoechst
HY-D2267JF646-Hoechst
HY-15559-01Hoechst 33342
HY-15558-01Hoechst 33258
HY-15619-01Hoechst S 769121
HY-15623-01Hoechst 33258 analog
HY-15627-01Hoechst 33342 analog
HY-15558A-01Hoechst 33258 (trihydrochloride)
HY-15559A-01Hoechst 33342 (trihydrochloride)
HY-15630Hoechst 33342 analog 2

Alternative Products

CatalogName
MF-0093343-01Hoechst 34580
MBS5755854Hoechst 34580 tetrahydrochloride
MF-0150116-01Hoechst 34580 trihydrochloride
A15115-5Hoechst 34580 5mg
A15115-25Hoechst 34580 25mg
A15115-100Hoechst 34580 100mg
A15115-2Hoechst 34580 2mg
A15115-10Hoechst 34580 10mg
A15115-50Hoechst 34580 50mg
A15115-10mM-DHoechst 34580 10mM * 1mL in DMSO

Popular Products