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Hoechst S 769121

CAT: 0804-HY-15619-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-15619-01Size:5 mg
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Description
Hoechst S 769121 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore, Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1].
CAS Number
74681-68-8
Product Name Alternative
Nuclear yellow
UNSPSC
12171500
Hazard Statement
H302, H315, H319, H335
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Nuclear-yellow.html
Purity
95.0
Solubility
H2O : ≥ 6 mg/mL
Smiles
[H]Cl.O=S(C1=CC=C(C2=NC3=CC(C4=NC5=CC(N6CCN(C)CC6)=CC=C5N4)=CC=C3N2)C=C1)(N)=O.[H]Cl.[H]Cl
Molecular Formula
C25H28Cl3N7O2S
Molecular Weight
596.96
Precautions
H302, H315, H319, H335
References & Citations
[1]Latt SA, Stetten G, Juergens LA, Recent developments in the detection of deoxyribonucleic acid synthesis by 33258 Hoechst fluorescence. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 23 (7) : 493-505.|[2]a b c "Hoechst Stains". Invitrogren (Molecular Probes) .|[3]Portugal J, Waring MJ. Assignment of DNA binding sites for 4',6-diamidine-2-phenylindole and bisbenzimide (Hoechst 33258) . A comparative footprinting study. Biochimica et Biophysica Acta 949
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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