SiR-Hoechst

CAT: 0804-HY-D2220Size: InquireDry Ice: NoHazardous: No
CAT#:0804-HY-D2220Size:Inquire
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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UNSPSC Description
SiR-Hoechst is a far-red fluorescent DNA probe being used widely for time-lapse imaging of living cells. SiR-Hoechst is minimally toxic at concentrations as high as 10-25 μM. SiR-Hoechst induces DNA damage responses and G2 arrest at concentrations well below 1 μM[1][2].
Target Antigen
DNA Stain
Type
Dye Reagents
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Solubility
10 mM in DMSO
Smiles
CN(CC1)CCN1C2=CC=C(N3)C(N=C3C4=CC=C(N5)C(N=C5C(C=C6)=CC=C6OCCCCNC(C(C=C7)=CC(C(C8=C([Si]9(C)C)C=C(C=C8)N(C)C)=C(C=C/%10)C9=CC%10=[N+](C)/C)=C7C([O-])=O)=O)=C4)=C2
Molecular Weight
950.21
References & Citations
[1]Sen O, et al. The live cell DNA stain SiR-Hoechst induces DNA damage responses and impairs cell cycle progression. Sci Rep. 2018 May 21;8(1):7898.|[2]Lukinavičius G, et al. SiR-Hoechst is a far-red DNA stain for live-cell nanoscopy. Nat Commun. 2015 Oct 1;6:8497.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported

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