JNJ-1289

• UNSPSC Description:

  JNJ-1289 is a potent, selective, competitive and allosteric human spermine oxidase (hSMOX) inhibitor (IC50: 50 nM). JNJ-1289 can be used in the research of polyamine catabolism, inflammation and cancers[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/jnj-1289.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  OC1=CC=C(C=C1)NC2=NC(C3=CN=C4C=CC=CN34)=CS2

• Molecular Weight:

  308.36

• References & Citations:

  [1]Elsie Diaz, et al. B Structure of human spermine oxidase in complex with a highly selective allosteric inhibitor. Commun Biol. 2022 Aug 5;5(1):787.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  792898-18-1