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JNJ-1289

CAT: 0804-HY-151115-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-151115-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JNJ-1289 is a potent, selective, competitive and allosteric human spermine oxidase (hSMOX) inhibitor (IC50: 50 nM) . JNJ-1289 can be used in the research of polyamine catabolism, inflammation and cancers[1].
CAS Number
792898-18-1
UNSPSC
12352005
Target
Smo
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/jnj-1289.html
Purity
98.06
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=C(C=C1)NC2=NC(C3=CN=C4C=CC=CN34)=CS2
Molecular Formula
C16H12N4OS
Molecular Weight
308.36
References & Citations
[1]Elsie Diaz, et al. B Structure of human spermine oxidase in complex with a highly selective allosteric inhibitor. Commun Biol. 2022 Aug 5;5 (1) :787.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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