Thalidomide-O-amido-PEG3-C2-NH2

Thalidomide-O-amido-PEG3-C2-NH2

• CAS Number: 1957236-20-2
• UNSPSC Description: Thalidomide-O-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
• Target Antigen: Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: Apoptosis;Autophagy;PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/E3_Ligase_Ligand-Linker_Conjugates_21.html
• Solubility: 10 mM in DMSO
• Smiles: NCCOCCOCCOCCNC(COC1=C(C2=CC=C1)C(N(C(CCC3=O)C(N3)=O)C2=O)=O)=O
• Molecular Weight: 506.51
• References & Citations: [1]Methods to induce targeted protein degradation through bifunctional molecules. WO 2017007612 A1
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported