Chymase-IN-1

Chymase-IN-1

• CAS Number: 862090-74-2
• UNSPSC Description: Chymase-IN-1 is a potent, selective, orally active, nonpeptide inhibitor of human mast cell chymase with an IC50 of 29 nM.
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/Chymase-IN-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NC1=CC=C2C=CC=CC2=C1)C(P(O)(O)=O)C3=CSC4=CC=C(Cl)C=C43
• Molecular Weight: 431.83
• References & Citations: [1]Greco MN, et al. Discovery of potent, selective, orally active, nonpeptide inhibitors of human mast cell chymase. J Med Chem. 2007 Apr 19;50(8):1727-30.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported