Chymase-IN-1

CAT: 0804-HY-100269Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-100269Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Chymase-IN-1 is a potent, selective, orally active, nonpeptide inhibitor of human mast cell chymase with an IC50 of 29 nM.
CAS Number
[862090-74-2]
UNSPSC
12352005
Target
Proteasome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Chymase-IN-1.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C2C=CC=CC2=C1)C(P(O)(O)=O)C3=CSC4=CC=C(Cl)C=C43
Molecular Formula
C20H15ClNO4PS
Molecular Weight
431.83
References & Citations
[1]Greco MN, et al. Discovery of potent, selective, orally active, nonpeptide inhibitors of human mast cell chymase. J Med Chem. 2007 Apr 19;50 (8) :1727-30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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