Chymase

• UNSPSC Description:

  Chymase is a protein-digester enzyme found primarily in mast cells (MC), fibroblasts, and vascular endothelial cells. Chymase is released into the extracellular stroma in the context of inflammatory signals, tissue injury and cellular stress. Chymase is also involved in angiotensin II (Ang II) production, which is used in cardiovascular disease studies[1].

• Target Antigen:

  Angiotensin Receptor

• Type:

  Enzyme

• Related Pathways:

  GPCR/G Protein

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/chymase.html

• Solubility:

  10 mM in DMSO

• Smiles:

  [Chymase]

• References & Citations:

  [1]Ahmad S, et al. Chymase inhibitors for the treatment of cardiac diseases: a patent review (2010-2018). Expert Opin Ther Pat. 2018 Nov;28(11):755-764.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  97501-92-3