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PID-9

CAT: 0804-HY-162369Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162369Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PID-9 is a P-glycoprotein inhibitor. PID-9 has multidrug resistance (MDR) reversal activity (IC50 = 0.1338 μM) and low toxicity. PID-9 inhibits the transport function of P-gp without downregulating P-gp expression[1].
UNSPSC
12352005
Target
P-glycoprotein
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pid-9.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(CCN2CC3=C(C=C(OC)C(OC)=C3)CC2)C=C1)C4=CC=CC=C4NC(C5=CC=C(C(N6CCN(C(CC78C[C@@]9([H])CC(C8)CC(C9)C7)=O)CC6)=O)C=C5)=O
Molecular Formula
C50H57N5O6
Molecular Weight
824.02
References & Citations
[1]Cao F, et al. Synthesis and evaluation of WK-X-34 derivatives as P-glycoprotein (P-gp/ABCB1) inhibitors for reversing multidrug resistance. RSC Med Chem. 2023 Dec 7;15 (2) :506-518.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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