PID-9

• UNSPSC Description:

  PID-9 is a P-glycoprotein inhibitor. PID-9 has multidrug resistance (MDR) reversal activity (IC50 = 0.1338 μM) and low toxicity. PID-9 inhibits the transport function of P-gp without downregulating P-gp expression[1].

• Target Antigen:

  P-glycoprotein

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pid-9.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NC1=CC=C(CCN2CC3=C(C=C(OC)C(OC)=C3)CC2)C=C1)C4=CC=CC=C4NC(C5=CC=C(C(N6CCN(C(CC78C[C@@]9([H])CC(C8)CC(C9)C7)=O)CC6)=O)C=C5)=O

• Molecular Weight:

  824.02

• References & Citations:

  [1]Cao F, et al. Synthesis and evaluation of WK-X-34 derivatives as P-glycoprotein (P-gp/ABCB1) inhibitors for reversing multidrug resistance. RSC Med Chem. 2023 Dec 7;15(2):506-518.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported