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PLCbeta3 (Phospho-Ser537) Colorimetric Cell-Based ELISA Kit

CAT: 0519-EKC2177Size: 1 Kit, Containing two 96 Well Plates and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC2177Size:1 Kit, Containing two 96 Well Plates and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The PLCbeta3 (Phospho-Ser537) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor PLCbeta3 (Phospho-Ser537) protein expression profile in cells. The kit can be used for measuring the relative amounts of PLCbeta3 (Phospho-Ser537) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on PLCbeta3 (Phospho-Ser537) .
Synonyms
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3; Phosphoinositide phospholipase C; Phospholipase C-beta-3; PLC-beta-3; PLCB3
Gene Name
PLCB3
UniProt
Q01970
Reactivity
Human, Mouse, Rat
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
Molecular Weight
138799 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
Subcellular Location
Membrane; Peripheral membrane protein.

UniProtKB · Q01970

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3

PLCB3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q01970
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PLCB3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.1.4.11
Processing
—
Secondary accessions
A5PKZ6, G5E960, Q8N1A4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Ligand

Calcium

Cellular component

CytoplasmMembraneNucleus

Disease

Dwarfism

Molecular function

HydrolaseTransducer

Biological process

Lipid degradationLipid metabolism