ADRB2 Colorimetric Cell-Based ELISA

• Description:

  The ADRB2 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor ADRB2 protein expression profile in cells. The kit can be used for measuring the relative amounts of ADRB2 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on ADRB2.

• Synonyms:

  Beta-2 adrenergic receptor; Beta-2 adrenoreceptor; Beta-2 adrenoceptor; ADRB2; ADRB2R, B2AR

• Gene Name:

  ADRB2

• UniProt:

  P07550

• Reactivity:

  Human, Mouse, Rat

• Applications:

  ELISA

• Detection Range:

  > 5000 cells/well

• Function:

  Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.

• Molecular Weight:

  46459 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Beta-2 adrenergic receptor

• Subcellular Location:

  Cell membrane; Multi- pass membrane protein. Early endosome. Colocalizes with VHL at the cell membrane (PubMed:19584355) . Activated receptors are internalized into endosomes prior to their degradation in lysosomes (PubMed:20559325) .