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ADCK4 Colorimetric Cell-Based ELISA

CAT: 0519-EKC1897Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC1897Size:1 Kit, containing one 96 Well Plate and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The ADCK4 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor ADCK4 protein expression profile in cells. The kit can be used for measuring the relative amounts of ADCK4 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on ADCK4.
Synonyms
Atypical kinase COQ8B, mitochondrial ;2.7.-.- ; AarF domain-containing protein kinase 4 ; Coenzyme Q protein 8B ; COQ8B ; ADCK4
Gene Name
COQ8B ADCK4
UniProt
Q96D53
Reactivity
Human, Mouse, Rat
Tissue Specificity
Widely expressed, including renal podocytes.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:24270420) . Its substrate specificity is unclear: does not show any protein kinase activity. Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway. Required for podocyte migration (PubMed:24270420) .
Molecular Weight
60069 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Atypical kinase COQ8B, mitochondrial
Subcellular Location
Mitochondrion membrane; Single-pass membrane protein. Cytoplasm, cytosol. Cell membrane.