DCLK2 Colorimetric Cell-Based ELISA

• Description:

  The DCLK2 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor DCLK2 protein expression profile in cells. The kit can be used for measuring the relative amounts of DCLK2 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on DCLK2.

• Synonyms:

  Serine/threonine-protein kinase DCLK2;2.7.11.1; CaMK-like CREB regulatory kinase 2; CL2; CLICK-II; CLICK2; Doublecortin domain-containing protein 3B; Doublecortin-like and CAM kinase-like 2; Doublecortin-like kinase 2; DCLK2; DCAMKL2, DCDC3B, DCK2

• Gene Name:

  DCLK2

• UniProt:

  Q8N568

• Reactivity:

  Human, Mouse

• Tissue Specificity:

  Expressed in the brain, heart and eyes.

• Applications:

  ELISA

• Detection Range:

  > 5000 cells/well

• Function:

  Protein kinase with a significantly reduced C (a2+) /CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm (By similarity) .

• Molecular Weight:

  83606 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Serine/threonine-protein kinase DCLK2

• Subcellular Location:

  Cytoplasm, cytoskeleton. Colocalizes with microtubules.