TLE4 Colorimetric Cell-Based ELISA

• Description:

  The TLE4 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor TLE4 protein expression profile in cells. The kit can be used for measuring the relative amounts of TLE4 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on TLE4.

• Synonyms:

  Transducin-like enhancer protein 4; Grg-4; Groucho-related protein 4; TLE4; GRG4, KIAA1261

• Gene Name:

  TLE4

• UniProt:

  Q04727

• Reactivity:

  Human, Mouse, Rat

• Tissue Specificity:

  In all tissues examined, mostly in brain, and muscle.

• Applications:

  ELISA

• Detection Range:

  > 5000 cells/well

• Function:

  Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression (By similarity) .

• Molecular Weight:

  83755 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Transducin-like enhancer protein 4

• Subcellular Location:

  Nucleus.