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SPI1 Colorimetric Cell-Based ELISA

CAT: 0519-EKC1684Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC1684Size:1 Kit, containing one 96 Well Plate and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The SPI1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor SPI1 protein expression profile in cells. The kit can be used for measuring the relative amounts of SPI1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on SPI1.
Synonyms
Transcription factor PU.1;31 kDa-transforming protein; SPI1
Gene Name
SPI1
UniProt
P17947
Reactivity
Human, Mouse, Rat
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Binds to the PU-box, a purine-rich DNA sequence (5'- GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B- cells. Also binds RNA and may modulate pre-mRNA splicing (By similarity) .
Molecular Weight
31083 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Transcription factor PU.1
Subcellular Location
Nucleus.

UniProtKB · P17947

Transcription factor PU.1

SPI1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P17947
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SPI1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorDevelopmental proteinDNA-bindingRNA-binding

Coding sequence diversity

Alternative splicing

Disease

Disease variantProto-oncogene

Cellular component

Nucleus

PTM

Phosphoprotein

Biological process

TranscriptionTranscription regulation

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