MKK3 Colorimetric Cell-Based ELISA Kit

• Description:

  The MKK3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor MKK3 protein expression profile in cells. The kit can be used for measuring the relative amounts of MKK3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on MKK3.

• Synonyms:

  Dual specificity mitogen-activated protein kinase kinase 3; kinase MKK3; MAP kinase kinase 3; MAP2K3; MAPK/ERK kinase 3; MAPKK 3; MEK3; MP2K3; PRKMK3

• Gene Name:

  MAP2K3

• UniProt:

  P46734

• Reactivity:

  Human, Mouse, Rat

• Tissue Specificity:

  Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14.

• Molecular Weight:

  39318 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Dual specificity mitogen-activated protein kinase kinase 3