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MKK3 Colorimetric Cell-Based ELISA Kit

CAT: 0519-EKC1371Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC1371Size:1 Kit, containing one 96 Well Plate and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The MKK3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor MKK3 protein expression profile in cells. The kit can be used for measuring the relative amounts of MKK3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on MKK3.
Synonyms
Dual specificity mitogen-activated protein kinase kinase 3; kinase MKK3; MAP kinase kinase 3; MAP2K3; MAPK/ERK kinase 3; MAPKK 3; MEK3; MP2K3; PRKMK3
Gene Name
MAP2K3
UniProt
P46734
Reactivity
Human, Mouse, Rat
Tissue Specificity
Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14.
Molecular Weight
39318 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Dual specificity mitogen-activated protein kinase kinase 3

UniProtKB · P46734

Dual specificity mitogen-activated protein kinase kinase 3

MP2K3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P46734
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MAP2K3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
MAP kinase kinase 3, MAPKK 3
EC number
2.7.12.2
Processing
—
Secondary accessions
B3KSK7, Q99441, Q9UE71, Q9UE72
Protein keywords

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Disease

Disease variant

Molecular function

KinaseSerine/threonine-protein kinaseTransferaseTyrosine-protein kinase

Technical term

Proteomics identificationReference proteome

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