MKK3 (Phospho-Thr222) Colorimetric Cell-Based ELISA Kit

• Description:

  The MKK3 (Phospho-Thr222) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor MKK3 (Phospho-Thr222) protein expression profile in cells. The kit can be used for measuring the relative amounts of MKK3 (Phospho-Thr222) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on MKK3 (Phospho-Thr222) .

• Synonyms:

  Dual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; MAPKK 3;2.7.12.2 ; MAPK/ERK kinase 3; MEK 3; Stress-activated protein kinase kinase 2; SAPK kinase 2; SAPKK-2; SAPKK2; MAP2K3; MEK3, MKK3, PRKMK3, SKK2

• Gene Name:

  MAP2K3

• UniProt:

  P46734

• Reactivity:

  Human, Mouse, Rat

• Tissue Specificity:

  Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.

• Applications:

  ELISA

• Detection Range:

  > 5000 cells/well

• Function:

  Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14.

• Molecular Weight:

  39318 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Dual specificity mitogen-activated protein kinase kinase 3