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GRK1 Colorimetric Cell-Based ELISA Kit

CAT: 0519-EKC1251Size: 1 Kit, containing one 96 Well Plate and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC1251Size:1 Kit, containing one 96 Well Plate and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The GRK1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor GRK1 protein expression profile in cells. The kit can be used for measuring the relative amounts of GRK1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on GRK1.
Synonyms
RHOK; RK; Rhodopsin kinase; kinase GRK1
Gene Name
GRK1
UniProt
Q15835
Reactivity
Human, Mouse, Rat
Tissue Specificity
Retinal-specific. Expressed in rods and cones cells.
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination.
Molecular Weight
63526 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Rhodopsin kinase
Subcellular Location
Membrane; Lipid-anchor.

UniProtKB · Q15835

Rhodopsin kinase GRK1

GRK1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q15835
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GRK1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
RK
EC number
2.7.11.14
Processing
Precursor
Secondary accessions
Q53X14
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell projectionMembrane

Disease

Congenital stationary night blindnessDisease variant

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

PTM

LipoproteinMethylationPhosphoproteinPrenylation

Biological process

Sensory transductionVision

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