GRK1 (Phospho-Ser21) Colorimetric Cell-Based ELISA Kit

• Description:

  The GRK1 (Phospho-Ser21) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor GRK1 (Phospho-Ser21) protein expression profile in cells. The kit can be used for measuring the relative amounts of GRK1 (Phospho-Ser21) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on GRK1 (Phospho-Ser21) .

• Synonyms:

  RHOK; RK; Rhodopsin kinase; kinase GRK1

• Gene Name:

  GRK1

• UniProt:

  Q15835

• Reactivity:

  Human, Mouse, Rat

• Tissue Specificity:

  Retinal-specific. Expressed in rods and cones cells.

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination.

• Molecular Weight:

  63526 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Rhodopsin kinase

• Subcellular Location:

  Membrane; Lipid-anchor.