Anti-HLA-DP/-DR (MHC II) HLA-DPB1 Monoclonal Antibody
CAT:
519-M00487
Size:
100 µg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-HLA-DP/-DR (MHC II) HLA-DPB1 Monoclonal Antibody
- Background: Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DR and DP. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36kDa) and a chain (27kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
- Description: Boster Bio Anti-HLA-DP/-DR (MHC II) HLA-DPB1 Monoclonal Antibody (Catalog # M00487). Tested in Flow Cytometry, IF, IHC applications. This antibody reacts with Human.
- Synonyms: HLA class II histocompatibility antigen, DP beta 1 chain;HLA class II histocompatibility antigen, DP (W4) beta chain;MHC class II antigen DPB1;HLA-DPB1;HLA-DP1B;
- CAS Number: 9007-83-4
- Gene Name: HLA-DPB1 & HLA-DRA
- UniProt: P04440; P01903
- Host: Mouse
- Reactivity: Human
- Immunogen: Human REH cells
- Clonality: Monoclonal
- Applications: Flow Cytometry, IF, IHC
- Purification: 200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.
- Concentration: Purified antibody with BSA and azide at 200ug/ml
- Form: Liquid
- Molecular Weight: 29159 MW
- Components: Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
- Storage Conditions: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Fragment: IgG3, kappa
- Clone ID: Clone: Clone: Bra-14