Anti-ANAPC5/Apc5 Antibody

• Background:

  Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
  
  Yu H., Science 279:1219-1222(1998).
  Bechtel S., BMC Genomics 8:399-399(2007).
  Kraft C., EMBO J. 22:6598-6609(2003).

• Description:

  Boster Bio Anti-ANAPC5/Apc5 Antibody (Catalog # A08280) . Tested in WB applications. This antibody reacts with Human.

• Synonyms:

  Anaphase-promoting complex subunit 5; APC5; Cyclosome subunit 5; ANAPC5; APC5

• Gene Name:

  ANAPC5

• UniProt:

  Q9UJX4

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Synthesized peptide derived from internal of human ANAPC5.

• Clonality:

  Polyclonal

• Applications:

  WB

• Field of Research:

  Cell Biology, Cell Cycle, Cell Division, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ubiquitin E3 Enzymes

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Dilution:

  Western blotting: 1:500~1:3000

• Form:

  Liquid

• Function:

  Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. .

• Molecular Weight:

  85077 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Anaphase-promoting complex subunit 5