Anti-GPR120 FFAR4 Antibody

• Description:

  Boster Bio Anti-GPR120 FFAR4 Antibody catalog # A04709. Tested in ELISA, IF, WB applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Free fatty acid receptor 4; G-protein coupled receptor 120; G-protein coupled receptor 129; G-protein coupled receptor GT01; G-protein coupled receptor PGR4; Omega-3 fatty acid receptor 1; FFAR4; GPR120, GPR129, O3FAR1, PGR4

• Gene Name:

  FFAR4

• UniProt:

  Q5NUL3

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human GPR120. AA range:221-270

• Clonality:

  Polyclonal

• Tissue Specificity:

  Abundant expression in the intestinal tract. Highly expressed in adipose tissue, small intestine and pancreas. .

• Applications:

  WB

• Purification:

  Immunogen affinity purified

• Concentration:

  1 mg/ml

• Dilution:

  WB, 1:500-1:2000

• Form:

  Liquid

• Function:

  Receptor for medium and long-chain free fatty acids (FFAs) . Signals via a G (q) /G (11) -coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti- inflammatory effects, particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2) /TAB1-dependent effect, but independent of the G (q) /G (11) -coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage- induced tissue inflammation. May mediate the taste of fatty acids. Mediates FFA-induced inhibition of apoptosis in enteroendocrine cells. May play a role in the regulation of adipocyte development and differentiation. .

• Molecular Weight:

  42241 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  IgG

• Other Gene Names:

  Free fatty acid receptor 4

• Subcellular Location:

  Cell membrane ; Multi-pass membrane protein . Colocalized with ARRB2 following DHA treatment. .