Mouse P-Cadherin-3 Cdh3 ELISA Kit PicoKine®

Mouse P-Cadherin-3 Cdh3 ELISA Kit PicoKine®

• Background: P-Cadherin, also known as Cadherin-3 (CDH3), is a protein that in humans is encoded by the CDH3 gene. This gene is a classical cadherin from the cadherin superfamily. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy. Cells expressing CDH3 also adhered to one another more tightly than the parental cell line.
• Description: Mouse P-Cadherin-3 Cdh3 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Cdh3 in cell culture supernatants and serum. Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.
• Synonyms: Cadherin-3;Placental cadherin;P-cadherin;Cdh3;Cdhp;
• CAS Number: 7732-18-5
• Gene Name: Cadherin-3
• Gene ID: 12560
• UniProt: P10287
• Reactivity: Mouse
• Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.
• Immunogen: Expression system for standard: NS0; Immunogen sequence: E100-G647
• Applications: ELISA
• Sample Type: cell culture supernatants and serum.
• Detection Range: 62.5 pg/ml - 4,000 pg/ml
• Sensitivity: <10 pg/ml
• Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
• Storage Conditions: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
• Calculated Molecular Weight: 90612 MW
• Reproducibility:

  Lots	Lot 1 (pg/ml)	Lot 2 (pg/ml)	Lot 3 (pg/ml)	Lot 4 (pg/ml)	Mean (pg/ml)	Standard Deviation	CV (%)
  Sample 1	198	204	177	182	190	11.09	5.8%
  Sample 2	571	533	614	577	573	28.71	5%
  Sample 3	1283	1280	1261	1323	1286	22.56	1.7%

  *number of samples for each test n=16.
• Specificity: Oligomeric forms of natural and recombinant mouse P-Cadherin