P-Cadherin (CDH3)

P-Cadherin (CDH3)

• Gene Name: [CDH3]
• NCBI Gene ID: 1001
• Reactivity: Human. Others not known.
• Storage Conditions: Antibody with azide - store at 2 to 8 °C.
  Antibody without azide - store at -20 to -80 °C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: Recognizes a protein of 116kDa, identified as P-Cadherin-1 (CDH3). It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congenital hypotrichosis with juvenile macular dystrophy.
• Other Gene Names: [CDH3; CDH3; CDHP; HJMD; PCAD; CDHP; P-cadherin]
• Short Name: [P-Cadherin (CDH3)]
• Other Product Names: [cadherin-3 isoform 2; Cadherin-3; cadherin-3; cadherin 3; Placental cadherin; P-cadherin]
• NCBI GI Number: 953953841
• NCBI Accession Number: NP_001304124.1
• NCBI GB Accession Number: NM_001317195.1
• Uniprot Accession Number: P22223