Human P-Cadherin-3 CDH3 ELISA Kit PicoKine®

Human P-Cadherin-3 CDH3 ELISA Kit PicoKine®

• Background: Cadherins are calcium-dependent cell-cell adhesion molecules that mediate cell-cell binding in a homophilic manner. They play an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Cadherin expression is regulated spatially as well as temporally. Cadherins are thought to play an important role in development and maintenance of tissues through selective cell-cell adhesion activity and may be involved also in the invasion and metastasis of malignant tumors. Cadherin regulates dendritic spine morphogenesis. A cadherin gene cluster is mapped to a region of chromosome 5 subject to frequent allelic loss in carcinoma. The standard product used in this kit is recombinant P-Cadherin with the molecular mass of 120-130Kda after glycosylation.
• Description: Human P-Cadherin-3 CDH3 ELISA Kit PicoKine® (96 Tests). Quantitate Human CDH3 in cell culture supernatants and serum. Sensitivity: 20pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.
• Synonyms: Cadherin-3;Placental cadherin;P-cadherin;CDH3;CDHP;
• CAS Number: 7732-18-5
• Gene Name: Cadherin-3
• Gene ID: 1001
• UniProt: P22223
• Reactivity: Human
• Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.
• Immunogen: Expression system for standard: NS0; Immunogen sequence: D108-G654
• Applications: ELISA
• Sample Type: cell culture supernatants and serum.
• Detection Range: 156 pg/ml - 10,000 pg/ml
• Sensitivity: <20 pg/ml
• Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
• Storage Conditions: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
• Calculated Molecular Weight: 91418 MW
• Reproducibility:

  Lots	Lot 1 (pg/ml)	Lot 2 (pg/ml)	Lot 3 (pg/ml)	Lot 4 (pg/ml)	Mean (pg/ml)	Standard Deviation	CV (%)
  Sample 1	262	177	211	243	223	7.28	3.3%
  Sample 2	1066	781	868	1158	968	63.71	6.6%
  Sample 3	3298	3822	3030	2921	3268	184.95	5.7%

  *number of samples for each test n=16.
• Specificity: Natural and recombinant human P-Cadherin