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BPTF-IN-BZ1

CAT: 0804-HY-132889-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-132889-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BPTF-IN-BZ1, a BPTF inhibitor, possesses a high potency (Kd = 6.3 nM) .
CAS Number
2766623-38-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bptf-in-bz1.html
Purity
98.31
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
NCCC1=CC=C(C=C1)NC2=C(C(N(C)N=C2)=O)Cl
Molecular Formula
C13H15ClN4O
Molecular Weight
278.74
Precautions
H302, H315, H319
References & Citations
[1]Zahid H, et al. New Design Rules for Developing Potent Cell-Active Inhibitors of the Nucleosome Remodeling Factor (NURF) via BPTF Bromodomain Inhibition. J Med Chem. 2021 Sep 23;64 (18) :13902-13917.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported